16. Dermal infiltrates of cells or substances

Infiltrates of cells or substances is not a classical reaction pattern but it helps to include it to describe those dermal conditions not covered by the other reaction patterns. The cellular infiltrates can be neutrophils in cellulitis and Sweet's syndrome, eosinophils in allergic reactions such as insect bites or Well's syndrome or lymphocytes in follicles as in lymphocytoma or lymphoma and plasma cells in syphillis and some mucosal diseases.. Substances in the dermis include mucin in the mucinoses and other disorders including lupus and necrobiosis lipoidica, calcium in ectopic calcification, some drugs such as minocycline, tatoo pigments, uric acid in gouty tophi and cholesterol and triglycerides in the xanthomas etc!